Your Guide to Altitude Sickness Tablets for High-Altitude Holiday Destinations
For many travellers, exploring high-altitude destinations is an exciting experience. However, altitude sickness, or acute mountain sickness, can become a concern at higher elevations where oxygen levels are lower. At Fermanagh Travel and Health Clinics, we advise travellers heading to certain destinations to consider taking altitude sickness tablets as a preventive measure. Here’s our guide to popular holiday spots where altitude sickness is common, helping you stay safe and enjoy your adventure to the fullest.
1. Cusco and Machu Picchu, Peru
Cusco, located at a striking 3,400 metres (11,200 feet) above sea level, serves as the gateway to Machu Picchu. Many travellers experience altitude sickness here, even if they feel fine initially. Cusco’s high altitude can lead to symptoms like dizziness, headaches, and shortness of breath. While Machu Picchu itself is lower, at 2,430 metres (7,970 feet), the transition can still cause symptoms, particularly if you plan to hike along the Inca Trail, which includes peaks of up to 4,200 metres (13,800 feet).
Advice: Travellers should consider taking altitude sickness tablets before arriving in Cusco, as the adjustment to the thin air can take time. Planning for an acclimatisation day before strenuous activities is also recommended.
2. La Paz, Bolivia
As one of the world’s highest cities, La Paz sits at an altitude of about 3,640 metres (11,942 feet). Many visitors arriving from lower altitudes struggle with La Paz’s lack of oxygen, especially if they’re flying in from sea level. Popular activities like exploring the city’s markets or hiking through the nearby mountains can become challenging when altitude sickness strikes.
Advice: Altitude sickness tablets, like acetazolamide, can help mitigate symptoms, allowing your body to adapt more smoothly. We also advise drinking plenty of water and avoiding alcohol for the first 24 hours, as it can worsen dehydration and exacerbate symptoms.

3. The Himalayas, Nepal
Nepal is home to some of the world’s highest mountains, including Mount Everest. Trekking in the Himalayas offers breath-taking scenery, but many popular trails, such as the Annapurna Circuit and Everest Base Camp trek, reach elevations above 4,000 metres (13,123 feet), where altitude sickness is a common risk.
Advice: Taking altitude sickness tablets in advance can make a significant difference, especially for multi-day treks where ascents can be steep and prolonged. Gradual acclimatisation and taking rest days are crucial, as is ensuring you have access to a travel clinic en route if needed.
4. Mount Kilimanjaro, Tanzania
Mount Kilimanjaro, the tallest mountain in Africa, rises to 5,895 metres (19,341 feet) at its summit. Climbers often feel the effects of altitude sickness, particularly on the final ascent, known as the “summit push,” where oxygen levels are particularly low. Although Kilimanjaro is a non-technical climb, altitude sickness can make the experience extremely challenging.
Advice: We highly recommend altitude sickness tablets for anyone climbing Kilimanjaro, especially those on shorter trekking schedules. The tablets help your body adjust and can alleviate symptoms during the more strenuous parts of the climb. A slower ascent, allowing for acclimatisation, is ideal.
5. Rocky Mountains, Colorado, USA
Many resorts in the Colorado Rockies, including Aspen, Breckenridge, and Vail, are situated above 2,500 metres (8,200 feet), and some mountain passes reach elevations of 3,500 metres (11,500 feet). Skiers and hikers alike may experience altitude sickness, particularly if they’re visiting from lower elevations and ascend quickly to the higher mountain peaks.
Advice: Altitude sickness tablets can ease symptoms, especially for those planning to ski or hike soon after arrival. Taking breaks and staying hydrated are helpful, as are avoiding caffeine and alcohol, which can contribute to dehydration at higher altitudes.
6. Swiss Alps, Switzerland
The Swiss Alps draw visitors for skiing, hiking, and mountaineering. While most tourist destinations in the Alps are below 2,500 metres (8,200 feet), some high-altitude spots, such as Zermatt and Jungfraujoch, can reach up to 3,454 metres (11,332 feet). Altitude sickness can affect some travellers here, particularly if they’re visiting multiple peaks or engaging in active sports.
Advice: Altitude sickness tablets are beneficial if you’re sensitive to high altitudes or have experienced symptoms before. For less experienced travellers, taking it slow is recommended, particularly during the initial days.

7. Puno and Lake Titicaca, Peru/Bolivia
At 3,812 metres (12,507 feet), Lake Titicaca is one of the highest navigable lakes in the world, straddling the border between Peru and Bolivia. The stunning views and unique islands make this a popular destination, but altitude sickness can catch visitors by surprise here, especially if they’re not acclimatised.
Advice: If you’re planning to travel to Lake Titicaca immediately after arriving in Cusco or La Paz, altitude sickness tablets can help ease the adjustment. Taking it easy for a day or two is also advised.
8. Quito, Ecuador
Quito, the capital city of Ecuador, sits at 2,850 metres (9,350 feet), making it one of the highest capital cities in the world. Travellers arriving by air often find it challenging to adjust to the thinner air, especially when exploring the city’s historical sites or venturing into the Andes.
Advice: For travellers susceptible to altitude sickness, altitude sickness tablets can make the adjustment easier. Acclimatisation for a day or two before strenuous activities, as well as avoiding alcohol initially, are good steps to take.
Choosing the Right Altitude Sickness Tablets with Fermanagh Travel and Health Clinics
Altitude sickness tablets, such as acetazolamide, can help prevent symptoms by assisting the body’s adaptation to lower oxygen levels. At Fermanagh Travel and Health Clinics, we recommend scheduling a consultation before your trip to discuss the appropriate dosage and usage based on your travel itinerary and health needs.
Remember, altitude sickness is often preventable with careful planning, gradual ascent, and hydration. However, if you’re heading to high-altitude destinations, altitude sickness tablets provide additional peace of mind, allowing you to focus on enjoying your travels.
Whether you’re visiting the peaks of Peru, trekking the Himalayas, or taking in the Rockies, our team at Fermanagh Travel and Health Clinics is here to ensure you’re well-prepared. Contact us for advice, and let’s make your high-altitude adventure as safe and enjoyable as possible.

This blog was written on behalf of Fermanagh Clinics by Pharmacy Mentor.
